How is cystic fibrosis treated?

Cystic fibrosis is a chronic, progressive disorder that can be treated but not cured. Treatment usually involves a combination of medications, nutritional support, physiotherapy, and other therapies. Medications used to treat cystic fibrosis include antibiotics to treat bacterial infections, mucus-thinning agents to help clear mucus from the airways, and bronchodilators to help open the airways and improve lung function. Nutritional support may include high-calorie diets, pancreatic enzyme replacement therapy, and vitamins and minerals. Physiotherapy is important to help clear mucus from the lungs, and may include chest percussion, postural drainage, and breathing exercises. Other therapies such as oxygen therapy, inhalers, and anti-inflammatory medications may also be used. Finally, lung transplantation may be an option for individuals with advanced cystic fibrosis.

In addition to the treatments listed above, there are also several medications in development that aim to target the underlying cause of cystic fibrosis. For example, ivacaftor and lumacaftor are two FDA-approved medications that target the CFTR gene, which is responsible for the disorder. Other drugs, such as gene therapy, are also being studied as potential treatments for cystic fibrosis. It is important for individuals with cystic fibrosis to work closely with their healthcare provider to discuss the best treatment options for their particular situation.